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Histidine residues in rabbit liver microsomal cytochrome P-450 2B4 control electron transfer from NADPH-cytochrome P-450 reductase and cytochrome b5.

Treatment of cytochrome P-450 2B4 (P-450 2B4) with diethylpyrocarbonate to introduce 10-11 equivalents of acylating agent per polypeptide chain resulted in the selective derivatization of histidine residues characterized by differential susceptibility toward the modifier. Second-derivative spectral...

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Détails bibliographiques
Auteurs principaux: Hlavica, P, Lehnerer, M, Eulitz, M
Format: Artigo
Langue:Inglês
Publié: 1996
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1217696/
https://ncbi.nlm.nih.gov/pubmed/8836129
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