Affinity for the nuclear compartment and expression during cell differentiation implicate phosphorylated Groucho/TLE1 forms of higher molecular mass in nuclear functions.

Lignende værker

• Cofactor-Activated Phosphorylation Is Required for Inhibition of Cortical Neuron Differentiation by Groucho/TLE1
  af: Buscarlet, Manuel, et al.
  Udgivet: (2009)
• Groucho/transducin-like enhancer of split (TLE) family members interact with the yeast transcriptional co-repressor SSN6 and mammalian SSN6-related proteins: implications for evolutionary conservation of transcription repression mechanisms.
  af: Grbavec, D, et al.
  Udgivet: (1999)
• Phosphorylation of Serine 239 of Groucho/TLE1 by Protein Kinase CK2 Is Important for Inhibition of Neuronal Differentiation
  af: Nuthall, Hugh N., et al.
  Udgivet: (2004)
• Transcription factors FOXG1 and Groucho/TLE promote glioblastoma growth
  af: Verginelli, Federica, et al.
  Udgivet: (2013)
• Role for Hes1-Induced Phosphorylation in Groucho-Mediated Transcriptional Repression
  af: Nuthall, Hugh N., et al.
  Udgivet: (2002)