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Cloning and biochemical characterization of the cyclophilin homologues from the free-living nematode Caenorhabditis elegans.

Cyclosporin A (CsA) is the most widely used immunosuppressive agent, whose properties are exerted via an interaction with cyclophilin, resulting in down-regulation of signal-transduction events in the T-cell. Cyclophilin is identical with peptidylprolyl cis-trans isomerase (PPI; EC 5.2.1.8), an enzy...

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Detalhes bibliográficos
Main Authors: Page, A P, MacNiven, K, Hengartner, M O
Formato: Artigo
Idioma:Inglês
Publicado em: 1996
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1217461/
https://ncbi.nlm.nih.gov/pubmed/8694762
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