Tissue Factor residue Asp44 regulates catalytic function of the bound proteinase Factor VIIa.

The coagulation pathways are initiated by the cell-surface receptor Tissue Factor (TF), which binds the serine proteinase coagulation Factor VIIa (VIIa), resulting in enhanced catalytic function, both amidolytic, towards small pseudo-substrates, and proteolytic, towards macromolecular substrates. He...

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Bibliografske podrobnosti
Main Authors: Kelly, C R, Schullek, J R, Ruf, W, Edgington, T S
Format: Artigo
Jezik:Inglês
Izdano: 1996
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1217163/
https://ncbi.nlm.nih.gov/pubmed/8670099
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