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Effect of a triplex-binding ligand on triple helix formation at a site within a natural DNA fragment.

We have used DNase I footprinting to examine the effect of a triplex-binding ligand on the formation of parallel intermolecular DNA triple helices at a mixed sequence target site contained within a natural DNA fragment (tyrT). In the presence of 10 microM ligand (N-[2-(dimethylamino)ethyl]-2-(naphth...

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Detalhes bibliográficos
Main Authors: Brown, P M, Drabble, A, Fox, K R
Formato: Artigo
Idioma:Inglês
Publicado em: 1996
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1217067/
https://ncbi.nlm.nih.gov/pubmed/8670052
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