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Human neural stem cells differentiate and promote locomotor recovery in spinal cord-injured mice

We report that prospectively isolated, human CNS stem cells grown as neurospheres (hCNS-SCns) survive, migrate, and express differentiation markers for neurons and oligodendrocytes after long-term engraftment in spinal cord-injured NOD-scid mice. hCNS-SCns engraftment was associated with locomotor r...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Cummings, Brian J., Uchida, Nobuko, Tamaki, Stanley J., Salazar, Desirée L., Hooshmand, Mitra, Summers, Robert, Gage, Fred H., Anderson, Aileen J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2005
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1216836/
https://ncbi.nlm.nih.gov/pubmed/16172374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0507063102
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