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Variation in structural location and amino acid conservation of functional sites in protein domain families

BACKGROUND: The functional sites of a protein present important information for determining its cellular function and are fundamental in drug design. Accordingly, accurate methods for the prediction of functional sites are of immense value. Most available methods are based on a set of homologous seq...

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Detalhes bibliográficos
Main Authors: Pils, Birgit, Copley, Richard R, Schultz, Jörg
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1215474/
https://ncbi.nlm.nih.gov/pubmed/16122386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-6-210
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