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Frequent Loss of the Active Site during Variant Surface Glycoprotein Expression Site Switching In Vitro in Trypanosoma brucei

African trypanosomes undergo antigenic variation of their variant surface glycoprotein (VSG) coat to avoid being killed by their mammalian hosts. The active VSG gene is located in one of many telomeric expression sites. Replacement of the VSG gene in the active site or switching between expression s...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Cross, Mike, Taylor, Martin C., Borst, Piet
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 1998
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC121476/
https://ncbi.nlm.nih.gov/pubmed/9418867
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