A Conserved Negative Regulatory Region in αPAK: Inhibition of PAK Kinases Reveals Their Morphological Roles Downstream of Cdc42 and Rac1

αPAK in a constitutively active form can exert morphological effects (E. Manser, H.-Y. Huang, T.-H. Loo, X.-Q. Chen, J.-M. Dong, T. Leung, and L. Lim, Mol. Cell. Biol. 17:1129–1143, 1997) resembling those of Cdc42(G12V). PAK family kinases, conserved from yeasts to humans, are directly activated by...

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Publié dans:	Mol Cell Biol
Auteurs principaux:	Zhao, Zhou-Shen, Manser, Edward, Chen, Xiang-Qun, Chong, Claire, Leung, Thomas, Lim, Louis
Format:	Artigo
Langue:	Inglês
Publié:	Taylor & Francis 1998
Sujets:	Cell Growth and Development
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC121452/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9528787/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.18.4.2153
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