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Mutation-Selection Balance in Multi-Locus Systems. I. Duplicate Gene Action

A theoretical model is presented that extends the case of selection against homozygous recessives counterbalanced by mutation to a system of n loci. This extension allows analysis of the role of gene duplication in the evolution of new function. The aspect of retention of function for sufficiently l...

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Autor principal: Pritchett-Ewing, Evelyn
Format: Artigo
Idioma:Inglês
Publicat: 1981
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1214449/
https://ncbi.nlm.nih.gov/pubmed/17249091
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