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Histidine Mutants Requiring Adenine: Selection of Mutants with Reduced hisG Expression in SALMONELLA TYPHIMURIUM

A method is described for the selection of Salmonella typhimurium mutants with reduced levels of hisG enzyme activity. This method is based on the fact that the hisG enzyme catalyzes the consumption of ATP in the first step of histidine biosynthesis. Normally, this reaction is closely regulated, bot...

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Библиографические подробности
Главные авторы: Johnston, H. Mark, Roth, John R.
Формат: Artigo
Язык:Inglês
Опубликовано: 1979
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC1213934/
https://ncbi.nlm.nih.gov/pubmed/387516
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