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Maintenance of Genetic Variability under the Joint Effect of Mutation, Selection and Random Drift

Formulae are developed for the distribution of allele frequencies (the frequency spectrum), the mean number of alleles in a sample, and the mean and variance of heterozygosity under mutation pressure and under either genic or recessive selection. Numerical computations are carried out by using these...

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Detalles Bibliográficos
Autor principal: Li, Wen-Hsiung
Formato: Artigo
Lenguaje:Inglês
Publicado: 1978
Materias:
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1213895/
https://ncbi.nlm.nih.gov/pubmed/17248867
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