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Regulation of Newly Evolved Enzymes. III Evolution of the ebg Repressor during Selection for Enhanced Lactase Activity

The evolution of lactose utilization by lacZ deletion strains of E. coli occurs via mutations in the ebg genes. We show that one kind of mutation in the regulatory gene ebgR results in a repressor which retains the ability to repress synthesis of ebg enzymes, but which permits 4.5-fold more ebg enzy...

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Autors principals: Hall, Barry G., Clarke, Norma D.
Format: Artigo
Idioma:Inglês
Publicat: 1977
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1213624/
https://ncbi.nlm.nih.gov/pubmed/324865
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