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An Attenuated LC16m8 Smallpox Vaccine: Analysis of Full-Genome Sequence and Induction of Immune Protection

The potential threat of smallpox bioterrorism has made urgent the development of lower-virulence vaccinia virus vaccines. An attenuated LC16m8 (m8) vaccine was developed in 1975 from the Lister strain used in the World Health Organization smallpox eradication program but was not used against endemic...

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Detalhes bibliográficos
Main Authors: Morikawa, Shigeru, Sakiyama, Tokuki, Hasegawa, Hideki, Saijo, Masayuki, Maeda, Akihiko, Kurane, Ichiro, Maeno, Go, Kimura, Junko, Hirama, Chie, Yoshida, Teruhiko, Asahi-Ozaki, Yasuko, Sata, Tetsutaro, Kurata, Takeshi, Kojima, Asato
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1212643/
https://ncbi.nlm.nih.gov/pubmed/16140764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.18.11873-11891.2005
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