Sialidase Activity of Influenza A Virus in an Endocytic Pathway Enhances Viral Replication

N2 neuraminidase (NA) genes of the 1957 and 1968 pandemic influenza virus strains possessed avian-like low-pH stability of sialidase activity, unlike most epidemic strains. We generated four reverse-genetics viruses from a genetic background of A/WSN/33 (H1N1) that included parental N2 NAs of 1968 p...

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Autores principales: Suzuki, Takashi, Takahashi, Tadanobu, Guo, Chao-Tan, Hidari, Kazuya I.-P. Jwa, Miyamoto, Daisei, Goto, Hideo, Kawaoka, Yoshihiro, Suzuki, Yasuo
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2005
Materias:
Virus-Cell Interactions
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1212606/
https://ncbi.nlm.nih.gov/pubmed/16140748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.18.11705-11715.2005
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