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Attenuation of Marek's Disease Virus by Deletion of Open Reading Frame RLORF4 but Not RLORF5a

Marek's disease (MD) in chickens is caused by the alphaherpesvirus MD virus (MDV) and is characterized by the development of lymphoblastoid tumors in multiple organs. The recent identification and cloning of RLORF4 and the finding that four of six attenuated strains of MDV contained deletions w...

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Detalhes bibliográficos
Main Authors: Jarosinski, Keith W., Osterrieder, Nikolaus, Nair, Venugopal K., Schat, Karel A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1212595/
https://ncbi.nlm.nih.gov/pubmed/16140742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.18.11647-11659.2005
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