Mitochondrial Cell Death Suppressors Carried by Human and Murine Cytomegalovirus Confer Resistance to Proteasome Inhibitor-Induced Apoptosis

Human cytomegalovirus carries a mitochondria-localized inhibitor of apoptosis (vMIA) that is conserved in primate cytomegaloviruses. We find that inactivating mutations within UL37x1, which encodes vMIA, do not substantially affect replication in TownevarATCC (Towne-BAC), a virus that carries a func...

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Bibliografiske detaljer
Main Authors: McCormick, A. Louise, Meiering, Christopher D., Smith, Geoffrey B., Mocarski, Edward S.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2005
Fag:
Virus-Cell Interactions
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1211555/
https://ncbi.nlm.nih.gov/pubmed/16160147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.19.12205-12217.2005
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