CD8(+) Lymphocytes Do Not Mediate Protection against Acute Superinfection 20 Days after Vaccination with a Live Attenuated Simian Immunodeficiency Virus

In order to test the hypothesis that CD8(+) cytotoxic T lymphocytes mediate protection against acute superinfection, we depleted >99% of CD8(+) lymphocytes in live attenuated simian immunodeficiency virus macC8 (SIVmacC8) vaccinees from the onset of vaccination, maintained that depletion for 20 d...

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Detalhes bibliográficos
Main Authors: Stebbings, Richard, Berry, Neil, Waldmann, Herman, Bird, Pru, Hale, Geoff, Stott, Jim, North, David, Hull, Robin, Hall, Joanna, Lines, Jenny, Brown, Stuart, D'Arcy, Nikki, Davis, Leanne, Elsley, William, Edwards, Cherry, Ferguson, Deborah, Allen, Jane, Almond, Neil
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1211523/
https://ncbi.nlm.nih.gov/pubmed/16160152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.19.12264-12272.2005
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