Genetic alteration of anxiety and stress-like behavior in mice lacking CaMKIV

Calcium-calmodulin-dependent protein kinase IV (CaMKIV) phosphorylates the major transcription factor cyclic AMP-response element binding protein (CREB), which plays a role in emotional behavior. Here, CaMKIV knockout mice (CaMKIV(-/-)) were tested in a battery of stress and anxiety-related behavior...

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Main Authors: Shum, Fanny WF, Ko, Shanelle W, Lee, Yong-Seok, Kaang, Bong-Kiun, Zhuo, Min
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2005
Assuntos:
Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1208947/
https://ncbi.nlm.nih.gov/pubmed/16102169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1744-8069-1-22
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