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Enhanced efficacy of gemcitabine in combination with anti-CD20 monoclonal antibody against CD20+ non-Hodgkin's lymphoma cell lines in vitro and in scid mice

BACKGROUND: Despite exciting new targeted therapeutics against non-Hodgkin's lymphoma (NHL), chemotherapy remains a cornerstone of therapy. While purine nucleoside analogs have significant activity in low grade NHL, the pyrimidine nucleoside analog gemcitabine has been less extensively studied,...

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Detalhes bibliográficos
Main Authors: Smith, Mitchell R, Joshi, Indira, Jin, Fang, Obasaju, Coleman
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1208862/
https://ncbi.nlm.nih.gov/pubmed/16109167
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-5-103
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