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Identification and Characterization of Genes That Interact with Lin-12 in Caenorhabditis Elegans

We identified and characterized 14 extragenic mutations that suppressed the dominant egg-laying defect of certain lin-12 gain-of-function mutations. These suppressors defined seven genes: sup-17, lag-2, sel-4, sel-5, sel-6, sel-7 and sel-8. Mutations in six of the genes are recessive suppressors, wh...

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Main Authors: Tax, F. E., Thomas, J. H., Ferguson, E. L., Horvitz, H. R.
Format: Artigo
Jezik:Inglês
Izdano: 1997
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Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1208340/
https://ncbi.nlm.nih.gov/pubmed/9409830
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