Rules of Donor Preference in Saccharomyces Mating-Type Gene Switching Revealed by a Competition Assay Involving Two Types of Recombination

Mating type (MAT) switching in Saccharomyces cerevisiae is initiated by a double-strand break (DSB) created at MAT by HO endonuclease. MATa cells activate the entire left arm of chromosome III; thus MATa preferentially recombines with the silent donor HML. In contrast, MATα cells inactivate the left...

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Bibliographic Details
Main Authors: Wu, X., Wu, C., Haber, J. E.
Format: Artigo
Language:Inglês
Published: 1997
Subjects:
Investigations
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1208166/
https://ncbi.nlm.nih.gov/pubmed/9335581
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