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Mutations in the Yeast Srb2 General Transcription Factor Suppress Hpr1-Induced Recombination and Show Defects in DNA Repair
We have obtained genetic and molecular evidence that the hrs2-1 mutation, isolated as a suppressor of the hyperrecombination phenotype of hpr1Δ, is in the SRB2 gene, which encodes a component of the RNA polII holoenzyme. A newly constructed srb2Δ allele restores the wild-type levels of deletions in...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
1996
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1207418/ https://ncbi.nlm.nih.gov/pubmed/8844143 |
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