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A Transgenic Mouse Assay for Agouti Protein Activity

The mouse agouti gene encodes an 131 amino acid paracrine signaling molecule that instructs hair follicle melanocytes to switch from making black to yellow pigment. Expression of agouti during the middle part of the hair growth cycle in wild-type mice produces a yellow band on an otherwise black hai...

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Bibliographic Details
Main Authors: Perry, W. L., Hustad, C. M., Swing, D. A., Jenkins, N. A., Copeland, N. G.
Format: Artigo
Language:Inglês
Published: 1995
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1206553/
https://ncbi.nlm.nih.gov/pubmed/7635291
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