Molecular Genetic Characterization of Six Recessive Viable Alleles of the Mouse Agouti Locus

The agouti locus on mouse chromosome 2 encodes a secreted cysteine-rich protein of 131 amino acids that acts as a molecular switch to instruct the melanocyte to make either yellow pigment (phaeomelanin) or black pigment (eumelanin). Mutations that up-regulate agouti expression are dominant to those...

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Main Authors: Hustad, C. M., Perry, W. L., Siracusa, L. D., Rasberry, C., Cobb, L., Cattanach, B. M., Kovatch, R., Copeland, N. G., Jenkins, N. A.
Format: Artigo
Sprog:Inglês
Udgivet: 1995
Fag:
Investigations
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1206552/
https://ncbi.nlm.nih.gov/pubmed/7635290
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