A Large-Scale Gene-Trap Screen for Insertional Mutations in Developmentally Regulated Genes in Mice

We have used a gene-trap vector and mouse embryonic stem (ES) cells to screen for insertional mutations in genes developmentally regulated at 8.5 days of embryogenesis (dpc). From 38,730 cell lines with vector insertions, 393 clonal integrations had disrupted active transcription units, as assayed b...

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Detalhes bibliográficos
Main Authors: Wurst, W., Rossant, J., Prideaux, V., Kownacka, M., Joyner, A., Hill, D. P., Guillemot, F., Gasca, S., Cado, D., Auerbach, A., Ang, S. L.
Formato: Artigo
Idioma:Inglês
Publicado em: 1995
Assuntos:
Investigations
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1206388/
https://ncbi.nlm.nih.gov/pubmed/7713439
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