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Gld-1, a Tumor Suppressor Gene Required for Oocyte Development in Caenorhabditis Elegans

We have characterized 31 mutations in the gld-1 (defective in germline development) gene of Caenorhabditis elegans. In gld-1(null) hermaphrodites, oogenesis is abolished and a germline tumor forms where oocyte development would normally occur. By contrast, gld-1(null) males are unaffected. The herma...

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Bibliographic Details
Main Authors: Francis, R., Barton, M. K., Kimble, J., Schedl, T.
Format: Artigo
Language:Inglês
Published: 1995
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1206368/
https://ncbi.nlm.nih.gov/pubmed/7713419
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