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Distance-Independent Inactivation of an Enhancer by the Suppressor of Hairy-Wing DNA-Binding Protein of Drosophila
When the gypsy retrotransposon of Drosophila inserts between an enhancer and promoter it prevents the enhancer from activating transcription. Enhancers are blocked because the protein (SUHW) encoded by the suppressor of Hairy-wing [su(Hw)] gene binds to gypsy. For example, gypsy insertions in an 85...
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Autor principal: | |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
1993
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1205581/ https://ncbi.nlm.nih.gov/pubmed/8375652 |
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