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Systematic Mutational Analysis of the Yeast Act1 Gene

We report the isolation and characterization of a synoptic set of site-directed mutations distributed throughout the single actin gene of Saccharomyces cerevisiae. Mutations were systematically targeted to the surface of the protein by identifying clusters of 2 or more charged residues in the primar...

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Detalles Bibliográficos
Main Authors: Wertman, K. F., Drubin, D. G., Botstein, D.
Formato: Artigo
Idioma:Inglês
Publicado: 1992
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1205140/
https://ncbi.nlm.nih.gov/pubmed/1427032
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