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Amino Acid Sequence Similarity between Gcn3 and Gcd2, Positive and Negative Translational Regulators of Gcn4: Evidence for Antagonism by Competition

The GCD2 gene product is required in conditions of amino acid sufficiency to repress the synthesis of GCN4, a transcriptional activator of amino acid biosynthetic genes in Saccharomyces cerevisiae. GCD2 is also required unconditionally for cell viability. The constitutive derepression of GCN4 expres...

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Detalhes bibliográficos
Main Authors: Paddon, C. J., Hannig, E. M., Hinnebusch, A. G.
Formato: Artigo
Idioma:Inglês
Publicado em: 1989
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1203729/
https://ncbi.nlm.nih.gov/pubmed/2668117
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