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Mutations in the Saccharomyces Cerevisiae Opi3 Gene: Effects on Phospholipid Methylation, Growth and Cross-Pathway Regulation of Inositol Synthesis

We report the isolation of two new opi3 mutants by EMS mutagenesis, and construction of an insertion allele in vitro using the cloned gene. We have demonstrated that the opi3 mutations cause a deficiency in the two terminal phospholipid N-methyltransferase (PLMT) activities required for the de novo...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: McGraw, P., Henry, S. A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1989
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1203704/
https://ncbi.nlm.nih.gov/pubmed/2670666
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