Mechanisms of Mutagenesis by Chloroacetaldehyde

A number of bifunctional chemical mutagens induce exocyclic DNA lesions. For example, 2-chloroacetaldehyde (CAA), a metabolite of vinyl chloride, readily reacts with single-stranded DNA to predominantly form etheno lesions. Here, we report on in vivo mutagenesis caused by CAA treatment of DNA in vit...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Jacobsen, J. S., Perkins, C. P., Callahan, J. T., Sambamurti, K., Humayun, M. Z.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 1989
Gaiak:
Investigations
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC1203611/
https://ncbi.nlm.nih.gov/pubmed/2659432
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