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Mutations Affecting the Trna-Splicing Endonuclease Activity of Saccharomyces Cerevisiae

Two unlinked mutations that alter the enzyme activity of tRNA-splicing endonuclease have been identified in yeast. The sen1-1 mutation, which maps on chromosome 12, causes temperature-sensitive growth, reduced in vitro endonuclease activity, and in vivo accumulation of unspliced pre-tRNAs. The sen2-...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Winey, M., Culbertson, M. R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1988
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1203316/
https://ncbi.nlm.nih.gov/pubmed/3284787
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