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Hph-1: A Mouse Mutant with Hereditary Hyperphenylalaninemia Induced by Ethylnitrosourea Mutagenesis

Ethylnitrosourea mutagenesis of spermatogonial stem cells and a three-generation breeding scheme were used to screen for recessive mutations that cause defects in phenylalanine metabolism leading to elevated serum levels of this amino acid. This paper describes the isolation of such a mutation, hph-...

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Bibliografski detalji
Glavni autori: Bode, V. C., McDonald, J. D., Guenet, J. L., Simon, D.
Format: Artigo
Jezik:Inglês
Izdano: 1988
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1203282/
https://ncbi.nlm.nih.gov/pubmed/3360305
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