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Genetic Evidence for Physical Interactions between Enzymes of Nucleotide Synthesis and Proteins Involved in DNA Replication in Bacteriophage T4
We have found that mutations in phage T4 genes 41 (five of five) and 61 (three of three) cause resistance to the folate analogue pyrimethamine that inhibits T4 dihydrofolate (FH(2)) reductase. These genes code for subunits of a T4 primase and are part of a putative T4 replication complex. In contras...
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| Autores principales: | , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
1984
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1202327/ https://ncbi.nlm.nih.gov/pubmed/6735173 |
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