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Choline Acetyltransferase-Deficient Mutants of the Nematode CAENORHABDITIS ELEGANS

We have identified five independent allelic mutations, defining the gene cha-1, that result in decreased choline acetyltransferase (ChAT) activity in Caenorhabditis elegans. Four of the mutant alleles, when homozygous, lead to ChAT reductions of>98%, as well as recessive phenotypes of uncoordinat...

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Autori principali: Rand, James B., Russell, Richard L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1984
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1202253/
https://ncbi.nlm.nih.gov/pubmed/6698395
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