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Role of PDZK1 in membrane expression of renal brush border ion exchangers

Na-H exchanger NHE3 and Cl-anion exchanger CFEX (SLC26A6, PAT1) play principal roles in the reabsorption of Na and Cl in the proximal tubule of the mammalian kidney. The mechanisms by which NHE3 and CFEX are localized to and maintained in the brush border of the proximal tubule are largely unknown....

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Autores principales: Thomson, R. Brent, Wang, Tong, Thomson, Benjamin R., Tarrats, Luis, Girardi, Adriana, Mentone, SueAnn, Soleimani, Manoocher, Kocher, Olivier, Aronson, Peter S.
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2005
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1201624/
https://ncbi.nlm.nih.gov/pubmed/16141316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0506578102
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