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An inhibitor of the F1 subunit of ATP synthase (IF1) modulates the activity of angiostatin on the endothelial cell surface

Angiostatin binds to endothelial cell (EC)-surface F(1)-F(0) ATP synthase, leading to inhibition of EC migration and proliferation during tumor angiogenesis. This has led to a search for angiostatin-mimetics specific for this enzyme. A naturally occurring protein that binds to the F1 subunit of ATP...

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Hlavní autoři: Burwick, Nick R., Wahl, Miriam L., Fang, Jun, Zhong, Zhaoxi, Capaldi, Roderick A., Kenan, Daniel J., Pizzo, Salvatore V.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2004
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1201548/
https://ncbi.nlm.nih.gov/pubmed/15528193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M405947200
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