Adjusting Data to Body Size: A Comparison of Methods as Applied to Quantitative Trait Loci Analysis of Musculoskeletal Phenotypes

The aim of this study was to compare three methods of adjusting skeletal data for body size and examine their use in QTL analyses. It was found that dividing skeletal phenotypes by body mass index induced erroneous QTL results. The preferred method of body size adjustment was multiple regression. IN...

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Main Authors: Lang, Dean H, Sharkey, Neil A, Lionikas, Arimantas, Mack, Holly A, Larsson, Lars, Vogler, George P, Vandenbergh, David J, Blizard, David A, Stout, Joseph T, Stitt, Joseph P, McClearn, Gerald E
Format: Artigo
Language:Inglês
Published: 2004
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1201530/
https://ncbi.nlm.nih.gov/pubmed/15824847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1359/JBMR.041224
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