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Biological, Biochemical and Kinetic Effects of Mutations of the Cardiomyopathy-loop of Dictyostelium Myosin II: Importance of Ala400
The cardiomyopathy (CM)-loop of the heavy chain of class-II myosins begins with a highly conserved Arg residue (whose mutation in human β-cardiac myosin II results in familial hypertrophic cardiomyopathy). The CM-loop of Dictyostelium myosin II (R397-Q407) is essential for its biological functions a...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1201472/ https://ncbi.nlm.nih.gov/pubmed/15897189 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M504453200 |
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