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Biological, Biochemical and Kinetic Effects of Mutations of the Cardiomyopathy-loop of Dictyostelium Myosin II: Importance of Ala400

The cardiomyopathy (CM)-loop of the heavy chain of class-II myosins begins with a highly conserved Arg residue (whose mutation in human β-cardiac myosin II results in familial hypertrophic cardiomyopathy). The CM-loop of Dictyostelium myosin II (R397-Q407) is essential for its biological functions a...

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Autori principali: Liu, Xiong, Shu, Shi, Kovács, Mihály, Korn, Edward D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2005
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1201472/
https://ncbi.nlm.nih.gov/pubmed/15897189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M504453200
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