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Evidence that the Tfg1/Tfg2 dimer interface of TFIIF lies near the active center of the RNA polymerase II initiation complex

The ssu71 alleles of the TFG1 gene, which encodes the largest subunit of TFIIF, were isolated as suppressors of a TFIIB defect that affects the accuracy of transcription start site selection in the yeast Saccharomyces cerevisiae. Here we report that ssu71-1 also suppresses the cell growth and start...

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Bibliographic Details
Main Authors: Freire-Picos, M. Angeles, Krishnamurthy, Shankarling, Sun, Zu-Wen, Hampsey, Michael
Format: Artigo
Language:Inglês
Published: Oxford University Press 2005
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1201334/
https://ncbi.nlm.nih.gov/pubmed/16147988
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gki825
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