Scrub Typhus Vaccine Candidate Kp r56 Induces Humoral and Cellular Immune Responses in Cynomolgus Monkeys

A truncated recombinant 56-kDa outer membrane protein of the Karp strain of Orientia tsutsugamushi (Kp r56) was evaluated in cynomolgus monkeys (Macaca fascicularis) for immunogenicity and safety as a vaccine candidate for the prevention of scrub typhus. This recombinant antigen induced strong humor...

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Main Authors: Chattopadhyay, Suchismita, Jiang, Ju, Chan, Teik-Chye, Manetz, T. Scott, Chao, Chien-Chung, Ching, Wei-Mei, Richards, Allen L.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2005
Assuntos:
Microbial Immunity and Vaccines
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1201273/
https://ncbi.nlm.nih.gov/pubmed/16041019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.73.8.5039-5047.2005
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