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Involvement of Ganglioside GM3 in G(2)/M Cell Cycle Arrest of Human Monocytic Cells Induced by Actinobacillus actinomycetemcomitans Cytolethal Distending Toxin
Actinobacillus actinomycetemcomitans produces a toxin called cytolethal distending toxin (CDT), which causes host cell DNA damage leading to the induction of DNA damage checkpoint pathways. CDT consists of three subunits, CdtA, CdtB, and CdtC. CdtB is the active subunit of CDT and exerts its effect...
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| Главные авторы: | , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Society for Microbiology
2005
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1201191/ https://ncbi.nlm.nih.gov/pubmed/16040998 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.73.8.4846-4852.2005 |
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