Recombinant Assay for Serodiagnosis of Lyme Disease Regardless of OspA Vaccination Status

All current seroassays using cultured Borrelia burgdorferi as their antigen source have been rendered obsolete by the recombinant OspA Lyme disease vaccine. OspA is the major outer surface protein expressed in cultured B. burgdorferi, and any seroassay that uses whole organisms as its antigen source...

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Autors principals: Gomes-Solecki, Maria J. C., Wormser, Gary P., Schriefer, Martin, Neuman, Glenn, Hannafey, Laura, Glass, John D., Dattwyler, Raymond J.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2002
Matèries:
Bacteriology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC120112/
https://ncbi.nlm.nih.gov/pubmed/11773115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JCM.40.1.193-197.2002
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