Recombinant Assay for Serodiagnosis of Lyme Disease Regardless of OspA Vaccination Status

All current seroassays using cultured Borrelia burgdorferi as their antigen source have been rendered obsolete by the recombinant OspA Lyme disease vaccine. OspA is the major outer surface protein expressed in cultured B. burgdorferi, and any seroassay that uses whole organisms as its antigen source...

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Main Authors: Gomes-Solecki, Maria J. C., Wormser, Gary P., Schriefer, Martin, Neuman, Glenn, Hannafey, Laura, Glass, John D., Dattwyler, Raymond J.
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Microbiology 2002
Ábhair:
Bacteriology
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC120112/
https://ncbi.nlm.nih.gov/pubmed/11773115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JCM.40.1.193-197.2002
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