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Role of specific hemagglutinin amino acids in the immunogenicity and protection of H5N1 influenza virus vaccines

If H5N1 influenza viruses become transmissible among humans, vaccination will offer the most effective option to limit their spread. Two human vaccine candidates recently generated by reverse genetics are based on antigenically different hemagglutinin (HA) glycoproteins derived from the A/HK/213/03...

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Hlavní autoři: Hoffmann, Erich, Lipatov, Aleksandr S., Webby, Richard J., Govorkova, Elena A., Webster, Robert G.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2005
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1200312/
https://ncbi.nlm.nih.gov/pubmed/16118277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0506416102
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