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Thermodynamically based DNA strand design

We describe a new algorithm for design of strand sets, for use in DNA computations or universal microarrays. Our algorithm can design sets that satisfy any of several thermodynamic and combinatorial constraints, which aim to maximize desired hybridizations between strands and their complements, whil...

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Detalhes bibliográficos
Main Authors: Tulpan, Dan, Andronescu, Mirela, Chang, Seo Bong, Shortreed, Michael R., Condon, Anne, Hoos, Holger H., Smith, Lloyd M.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1199561/
https://ncbi.nlm.nih.gov/pubmed/16145053
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gki773
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