Opsonophagocytosis of Fluorescent Polystyrene Beads Coupled to Neisseria meningitidis Serogroup A, C, Y, or W135 Polysaccharide Correlates with Serum Bactericidal Activity

We developed a polysaccharide-specific flow cytometric opsonophagocytic assay (OPA) for the simultaneous measurement of functional antibody to Neisseria meningitidis serogroups A, C, Y, and W135. OPA titers significantly correlated with serum bactericidal assay titers for all serogroups tested (mean...

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Main Authors: Martinez, Joseph, Pilishvili, Tamara, Barnard, Suzanne, Caba, Joseph, Spear, Willie, Romero-Steiner, Sandra, Carlone, George M.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2002
Teme:
Antibodies and Mediators of Immunity
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC119948/
https://ncbi.nlm.nih.gov/pubmed/11874898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CDLI.9.2.485-488.2002
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