Opsonophagocytosis of Fluorescent Polystyrene Beads Coupled to Neisseria meningitidis Serogroup A, C, Y, or W135 Polysaccharide Correlates with Serum Bactericidal Activity

We developed a polysaccharide-specific flow cytometric opsonophagocytic assay (OPA) for the simultaneous measurement of functional antibody to Neisseria meningitidis serogroups A, C, Y, and W135. OPA titers significantly correlated with serum bactericidal assay titers for all serogroups tested (mean...

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Detalhes bibliográficos
Main Authors: Martinez, Joseph, Pilishvili, Tamara, Barnard, Suzanne, Caba, Joseph, Spear, Willie, Romero-Steiner, Sandra, Carlone, George M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
Assuntos:
Antibodies and Mediators of Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC119948/
https://ncbi.nlm.nih.gov/pubmed/11874898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CDLI.9.2.485-488.2002
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