Localization of a Type 1 Diabetes Locus in the IL2RA/CD25 Region by Use of Tag Single-Nucleotide Polymorphisms

As part of an ongoing search for genes associated with type 1 diabetes (T1D), a common autoimmune disease, we tested the biological candidate gene IL2RA (CD25), which encodes a subunit (IL-2Rα) of the high-affinity interleukin-2 (IL-2) receptor complex. We employed a tag single-nucleotide polymorphi...

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Hauptverfasser: Vella, Adrian, Cooper, Jason D., Lowe, Christopher E., Walker, Neil, Nutland, Sarah, Widmer, Barry, Jones, Richard, Ring, Susan M., McArdle, Wendy, Pembrey, Marcus E., Strachan, David P., Dunger, David B., Twells, Rebecca C. J., Clayton, David G., Todd, John A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The American Society of Human Genetics 2005
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1199367/
https://ncbi.nlm.nih.gov/pubmed/15776395
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