Antigen-Driven T-Cell Selection in Patients with Cervical Cancer as Evidenced by T-Cell Receptor Analysis and Recognition of Autologous Tumor

We characterized the T-cell receptor (TCR) repertoire in freshly harvested tumor lesions, in short-term-expanded CD4(+) tumor infiltrating lymphocytes (TIL) as well as in CD4(+) and CD8(+) peripheral blood lymphocytes (PBL) from three patients with cervical cancer. Skewing of the T-cell repertoire a...

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Detalhes bibliográficos
Main Authors: Pilch, H., Höhn, H., Neukirch, C., Freitag, K., Knapstein, P. G., Tanner, B., Maeurer, M. J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
Assuntos:
Experimental Clinical Investigation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC119930/
https://ncbi.nlm.nih.gov/pubmed/11874862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CDLI.9.2.267-278.2002
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