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Denervation increases the degradation rate of acetylcholine receptors at end-plates in vivo and in vitro.

We have studied the effect of denervation on the degradation of the existing junctional acetylcholine (ACh) receptors at end-plates in rat muscles. ACh receptors were labelled by injecting animals with iodinated alpha-bungarotoxin (I-alpha BT); 1 day later the left hemidiaphragm was denervated. The...

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Détails bibliographiques
Auteurs principaux: Bevan, S, Steinbach, J H
Format: Artigo
Langue:Inglês
Publié: 1983
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1198963/
https://ncbi.nlm.nih.gov/pubmed/6875905
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